Toxicity of group B Streptococcus agalactiae in adult rats

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Toxicity of group B Streptococcus agalactiae in adult rats.

Several strains of group B Streptococcus agalactiae were found to be lethal for young adult rats. When bacteria were heat killed and then injected intraperitoneally into rats, rapid death (14 to 18 h) of the rats occurred, characterized by labored breathing, hemolyzed serum, hemoglobinuria, and subungual hemorrhages. Sections of tissues from these rats failed to reveal the cause of death. Rats ...

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Postsplenectomy sepsis caused by group B streptococcus (S. agalactiae) in an adult patient with diabetes mellitus.

Overwhelming postsplenectomy infection (OPSI) due to group B streptococcus developed in an insulin-dependent diabetic patient. The illness began with nonspecific symptoms, followed rapidly by hypotension and disseminated intravascular coagulation. The early institution of appropriate antibiotics, fluid replacement and pressor agents resulted in a favorable clinical outcome. The association of g...

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In vitro Activity of Solithromycin (CEM-101) Against Macrolide-resistant Streptococcus agalactiae (Group B Streptococcus)

Introduction: Streptococcus agalactiae (Group B Streptococcus or GBS), now recognized as a qualified infectious disease pathogen (QIDP) by the FDA, remains the leading cause of morbidity and mortality among infants in the United States. Although the incidence of GBS in pregnancy has decreased, penicillin and ampicillin minimal inhibitory concentrations (MICs) for GBS have risen, requiring highe...

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Use of a serotype-specific DNA microarray for identification of group B Streptococcus (Streptococcus agalactiae).

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1985

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.48.2.560-564.1985